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所在位置:所有产品 > 抗体抗原 > 一抗 > IRF3抗体
IRF3抗体图片
产品货号:
Z37428
中文名称:
IRF3抗体
英文名称:
Anti-IRF3 Antibody (Clone#OTI4D4)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-IRF3 Antibody (Clone#OTI4D4)
指标别名interferon regulatory factor 3;IRF 3;IRF3
克隆性Monoclonal
检验物种human
应用范围WB,IHC,IF,FCM
基因名称IRF3
克隆号OTI4D4
抗体来源Mouse
抗体类型IgG2a
免疫原Full length human recombinant protein of human IRF3 (NP_001562) produced in HEK293T cell.
实际分子量47KD
成分PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide.
纯化方式Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度500μg/mL
产品形态溶液
保存条件Stable for 12 months from date of receipt.Store at -20℃ as received.
背景资料IRF3(interferon regulatory factor 3)?is a member of the interferon regulatory transcription factor(IRF) family.The IRF3 gene is mapped on 19q13.33.IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with?CREBBP.IRF3 plays an important role in the?innate immune system's response to?viral infection.Aggregated?MAVS?have been found to activate IRF3 dimerization.Although?IRF3?increased transcriptional activity from an ISRE-containing promoter,expression of?IRF3?as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase(CAT) reporter gene containing repeats of the Gal4-binding sites.?Translocation of?IRF3?was accompanied by an increase in serine and threonine phosphorylation.?The transcriptional activators CREBBP and EP300 coimmunoprecipitated with?IRF3?only subsequent to viral infection,and the authors stated that these are also subunits of DRAF1.
Uniprot IDQ14653
基因名全称interferon regulatory factor 3
蛋白名全称Interferon regulatory factor 3
推荐稀释比
Western blot (WB) 1:1000~2000
Immunohistochemistry in paraffin section (IHC) 1:50
Immunofluorescence (IF) 1:100
Flow cytometry (FCM) 1:100

相关搜索:IRF3抗体IRF3单抗Anti-IRF3 Antibody (Clone#OTI4D4)
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